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Updated: Jun 28, 2026

Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
Autologous buccal mucosa vulvovaginoplasty for high urogenital sinus
Mindy L Samuelson1, Linda A Baker
1Department of Urology, University of Texas Southwestern Medical Center at Dallas, Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390-9110, USA.
Abstract:
Feminizing genitoplasty for mid to high urogenital sinus confluence is challenging surgery, especially in the postpubertal patient. We report a surgical alternative for a complex postpubertal case with scarce perineal tissue. An autologous buccal mucosa vulvovaginoplasty was performed in a postpubertal patient with adrenogenital syndrome, permitting vaginal lengthening, creation of labia minora and minimal urethral dissection. This surgical approach avoided female hypospadias, as seen with the total urogenital sinus mobilization repair, and the risks of extensive urethral dissection, seen with the vaginal pull-through procedure, but yet solved the dilemma of mucosal coverage for the vulva and anterior vaginal wall. Buccal mucosa is a natural replacement for the female vulvar and vaginal glabrous skin, and is an excellent adjunct or alternative in challenging reconstructions.
