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Acanthosis nigricans and a rectal carcinoid.
K T Schmidt1, M C Massa, S E Welykyj
1Department of Medicine, Loyola University Medical Center, Maywood, IL 60153.
Journal of the American Academy of Dermatology
|August 1, 1991
Summary
Malignant acanthosis nigricans can signal gastrointestinal cancers. This case highlights its association with a rectal carcinoid tumor, emphasizing the need for thorough cancer screening in patients with this skin condition.
Area of Science:
- Dermatology
- Oncology
- Gastroenterology
Background:
- Malignant acanthosis nigricans (MAN) is a skin condition often linked to gastrointestinal adenocarcinomas.
- MAN can also be associated with neuroendocrine tumors, including carcinoid tumors.
- The skin changes can manifest before, during, or after the diagnosis of the primary malignancy.
Observation:
- A patient presented with new-onset acanthosis nigricans.
- Diagnostic evaluation for the acanthosis nigricans revealed an asymptomatic carcinoid tumor in the rectum.
Findings:
- This case represents the first documented instance of acanthosis nigricans associated with a rectal carcinoid tumor.
- The findings suggest a potential link between MAN and neuroendocrine tumors of the rectum.
Implications:
- The presence of acanthosis nigricans warrants a comprehensive investigation for underlying malignancies, including rare neuroendocrine tumors.
- Early detection of associated cancers through thorough evaluation of MAN can improve patient outcomes.
- This case expands the known spectrum of tumors associated with malignant acanthosis nigricans.