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Updated: Jun 28, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
[Effects of omega 3 supplementation in pregnant women]
O Picone1, A Marszalek, J-L Servely
1Service de gynécologie-obstétrique, hôpital Antoine-Béclère, AP-HP, 157, rue de la porte de Trivaux, 92141 Clamart, France. olivier.picone@abc.aphp.fr
Abstract:
Maternal nutrition is a major environmental factor, which can be modified and can affect fetal growth and development with potential long-term consequences. There is currently a strong mediatic pressure for supplementing diets with omega 3 fatty acids. Nevertheless, if beneficial effects seem to be confirmed in adults and in animal models, the evidence for favourable effects of omega 3 supplementation in pregnant women are less obvious. Indeed, there is a trend showing a positive effect on cerebral development, but long term effects have not been demonstrated and both the quantity of omega 3 and the omega 3:omega 6 ratios are not precisely determined. Numerous studies are needed, both in pregnant animal models and in patients, to unravel these effects.
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