Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Multi-species Conserved Sequences

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved DNA...

Applications of Molecular Taxonomy

Applications of Molecular Taxonomy

Molecular taxonomy has revolutionized the understanding and classification of bacteria, providing precise insights into their diversity, evolutionary relationships, and ecological roles. By utilizing molecular techniques such as DNA sequencing and fingerprinting, researchers have made significant strides in various fields related to bacterial studies.Resolving Taxonomic AmbiguitiesMolecular taxonomy has been instrumental in distinguishing closely related bacterial species initially thought to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Synthetic Mimotopes of Salivary Peptides against SARS-CoV-2 In Vitro.

Journal of dental research·2025

Same author

Effect of berberine associated with photodynamic therapy in cell lines.

Photodiagnosis and photodynamic therapy·2020

Same author

Insights into the antiviral activity of phospholipases A<sub>2</sub> (PLA<sub>2</sub>s) from snake venoms.

International journal of biological macromolecules·2020

Same author

Adverse birth outcomes associated with Zika virus exposure during pregnancy in São José do Rio Preto, Brazil.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2017

Same author

Natural compounds isolated from Brazilian plants are potent inhibitors of hepatitis C virus replication in vitro.

Antiviral research·2015

Same author

Acupuncture needles can carry hepatitis C virus.

Infection control and hospital epidemiology·2014

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

AQRNA-seq for Quantifying Small RNAs

AQRNA-seq for Quantifying Small RNAs

Published on: February 2, 2024

Routine libraries for pattern recognition in quasispecies.

E A Marucci¹, G F D Zafalon, A C G Jardim

¹Laboratório de Bioinformática, Universidade Estadual Paulista, São José do Rio Preto, SP, Brasil.

Genetics and Molecular Research : GMR

|October 25, 2008

Summary

This study introduces new bioinformatics software to analyze complex quasispecies population diversity. The tool helps identify genome regions prone to mutations and potential hot spots for evolutionary changes.

More Related Videos

Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response

Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response

Published on: August 10, 2017

Related Experiment Videos

Last Updated: Jun 28, 2026

AQRNA-seq for Quantifying Small RNAs

AQRNA-seq for Quantifying Small RNAs

Published on: February 2, 2024

Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response

Measuring mRNA Levels Over Time During the Yeast S. cerevisiae Hypoxic Response

Published on: August 10, 2017

Area of Science:

Bioinformatics
Computational Biology
Virology

Background:

Biological research generates large datasets (nucleotide/amino acid sequences) requiring computational analysis.
Manual analysis of complex biological data, like quasispecies, is often infeasible.
Bioinformatics tools are essential for studying quasispecies dynamics and evolution.

Purpose of the Study:

To develop a novel software tool for evaluating population diversity in quasispecies.
To aid biologists in analyzing complex sequence data.
To identify genomic regions susceptible to variation and potential mutation hotspots.

Main Methods:

Development of specialized bioinformatics software.
Application of computational algorithms for sequence analysis.
Focus on population diversity metrics within quasispecies.

Main Results:

A new software tool for quasispecies diversity analysis has been created.
The software facilitates the identification of genome regions prone to changes.
Potential mutation hotspots within quasispecies genomes can be localized.

Conclusions:

The developed software addresses the need for efficient computational tools in quasispecies research.
This tool aids in understanding viral evolution and genetic diversity.
It provides insights into genome regions critical for quasispecies adaptation.