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Updated: Jun 28, 2026

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature
Published on: October 14, 2022
Lumican, a small leucine-rich proteoglycan
Dragana Nikitovic1, Paulos Katonis, Aristidis Tsatsakis
1Lab of Histology, Medical School, University of Crete, Heraklion, Greece.
Abstract:
Lumican belongs to the family of small leucine-rich repeat proteoglycans. Recent studies have shown that lumican participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. The expression of lumican has been correlated to the growth and metastasis of various malignancies; however, its exact role in tumorogenesis remains elusive. This review focuses upon the role of lumican in cell biology, providing insights into molecular mechanisms that lumican likely utilizes to control processes relevant to tumorogenesis.
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