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Identification of alpha amylase inhibitors from Syzygium cumini Linn seeds

K Karthic1, K S Kirthiram, S Sadasivam

  • 1Department of Biotechnology, Kumaraguru College of Technology, Coimbatore 641 006, India.

Indian Journal of Experimental Biology
|October 28, 2008
PubMed

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α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
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