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Related Experiment Video

Updated: Jun 28, 2026

A Mouse Distraction Osteogenesis Model
04:24

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

[Soft tissue profile changes in micrognathia after distraction osteogenesis].

Xiao-Hui Fu1, Jan Chen, Fei-Yun Ping

  • 1Department of Oral and Maxillofacial Surgery, 2nd Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou 310009, China.

Zhonghua Zheng Xing Wai Ke Za Zhi = Zhonghua Zhengxing Waike Zazhi = Chinese Journal of Plastic Surgery
|October 28, 2008
PubMed
Summary

Distraction osteogenesis significantly improves facial profiles in severe micrognathia (underdeveloped jaw). This surgical technique enhances soft tissue contours in the middle and lower face, leading to better aesthetic outcomes.

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Area of Science:

  • Craniofacial surgery
  • Orthognathic surgery
  • Regenerative medicine

Context:

  • Severe micrognathia presents significant aesthetic and functional challenges.
  • Current treatment options for micrognathia have limitations.
  • Distraction osteogenesis offers a novel approach to mandibular reconstruction.

Purpose:

  • To evaluate the efficacy of distraction osteogenesis in correcting severe micrognathia.
  • To compare pre- and post-operative facial profiles and mentolabial relationships.
  • To assess changes in bony and soft tissue cephalometry following the procedure.

Summary:

  • Sixteen patients with severe micrognathia underwent mandibular distraction osteogenesis combined with temporomandibular joint plasty and fasciomuscular flap transfer.

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Last Updated: Jun 28, 2026

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  • Distraction commenced on the 5th postoperative day at 0.8 mm/day.
  • Significant improvements were observed in facial convexity, lower facial height, lip length, inter-labial distance, lip-to-esthetic plane distance, mentolabial crease depth, and mental soft tissue thickness.

    • Impact:

    • Mandibular distraction osteogenesis effectively improves the soft tissue profile of the middle and lower face in patients with severe micrognathia.
    • The procedure leads to significant aesthetic enhancements.
    • This technique provides a viable surgical solution for complex craniofacial deformities.