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Increased Body Temperature

Increased Body Temperature

A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

Types of Fever

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:

Acute Pyelonephritis I: Introduction

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...

Methods of reducing fever

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

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Related Experiment Video

Updated: Jun 28, 2026

Examination of Pyroptosis by Flow Cytometry

Examination of Pyroptosis by Flow Cytometry

Published on: May 31, 2024

Folate deficiency presenting as pyrexia: a case report.

Aran Singanayagam¹, Nisal Gange, Anika Singanayagam

¹Department of Acute General Medicine, John Radcliffe Hospital, Headley way, Headington, Oxford, OX3 9DU, UK. aransinga@gmail.com.

|October 28, 2008

Summary

Severe folate deficiency can cause pyrexia (fever) in adults, leading to megaloblastic anemia. This reversible condition should be considered in unexplained fever cases.

Related Experiment Videos

Last Updated: Jun 28, 2026

Examination of Pyroptosis by Flow Cytometry

Examination of Pyroptosis by Flow Cytometry

Published on: May 31, 2024

Area of Science:

Internal Medicine
Hematology

Background:

Pyrexia (fever) is commonly caused by infections or inflammation.
Folate deficiency typically presents with hematological abnormalities, not fever.

Purpose of the Study:

To report a case of pyrexia secondary to severe folate deficiency.
To highlight folate deficiency as a potential, reversible cause of unexplained fever.

Main Methods:

Case report of a 29-year-old male with pyrexia.
Exclusion of infectious and inflammatory causes.
Documentation of temperature and hematological findings.

Main Results:

The patient's pyrexia resolved with folate supplementation.
Megaloblastic anemia secondary to severe folate deficiency was diagnosed.
Pathophysiological mechanisms linking folate deficiency and pyrexia were proposed.

Conclusions:

Folate deficiency is an uncommon but reversible cause of pyrexia.
Consider folate deficiency in patients with unexplained fever and megaloblastic anemia.