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Published on: June 11, 2019
[Primary Salmonella vascular graft infection and conservative treatment]
1Unité de maladies infectieuses, CHRU Huriez 5E, 2, avenue Oscar-Lambret, 59037 Lille cedex, France. gberaud@hotmail.com
Abstract:
The authors report an unusual case of prosthetic vascular graft infection due to Salmonellatyphimurium. The initial treatment combined antibiotherapy and surgical replacement of the arteriovenous graft. The infection relapsed within 6 weeks and was successfully treated with antibiotics only. Five cases of vascular graft infection due to Salmonella have been reported so far, but only one occurred in a previously healthy man and was not related to local infection, but to bacteremic seeding. Specific features of vascular graft infection and importance of prevention are discussed.
Insights
Salmonella typhimurium can infect prosthetic vascular grafts, requiring combined antibiotic and surgical treatment. In this case, a relapse was successfully managed with antibiotics alone, highlighting treatment flexibility for graft infections.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Microbiology
Background:
- Prosthetic vascular graft infections pose significant clinical challenges.
- Salmonella species are an uncommon cause of graft infections, often associated with bacteremia.
Observation:
- An unusual case of prosthetic arteriovenous graft infection caused by Salmonella typhimurium is presented.
- Initial management involved antibiotherapy and surgical graft replacement.
- The patient experienced a relapse within six weeks post-surgery.
Findings:
- Successful treatment of the relapsed graft infection was achieved with antibiotics alone.
- This case adds to the limited literature on Salmonella-related vascular graft infections.
- The infection in this previously healthy individual was attributed to bacteremic seeding.
Implications:
- The findings suggest that antibiotic-only therapy may be effective for relapsed Salmonella graft infections.
- Highlights the importance of considering Salmonella in the differential diagnosis of vascular graft infections.
- Emphasizes the need for preventative strategies against graft infections, particularly in immunocompetent hosts.