An efficient synthesis of bis(indolyl)methanes and evaluation of their antimicrobial activities
Ahmed Kamal1, M Naseer A Khan, K Srinivasa Reddy
1Division of Organic Chemistry, Biotransformation Laboratory, Indian Institute of Chemical Technology, Hyderabad, India. ahmedkamal@iict.res.in
Journal of Enzyme Inhibition and Medicinal Chemistry
|October 28, 2008
Abstract:
A versatile and efficient method has been developed for the synthesis of bis(indolyl)methanes by using aluminium triflate (0.5 mol%) as a novel catalyst. Further, some of the synthesized compounds were evaluated for their efficacy as antibacterial and antifungal activities. Most of the compounds have shown moderate to good inhibitory activity.
