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Updated: Jun 28, 2026

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury
Published on: February 23, 2015
Managing acute spinal cord injuries
Stephanie A Kube1, Natasha J Olby
1VCA South Shore Animal Hospital, Weymouth, MA, USA.
Abstract:
Acute spinal cord injuries commonly seen in veterinary patients include vascular, compressive, and concussive injuries. Vascular lesions, or infracts, are usually caused by fibrocartilagenous emboli. Concussive and compressive injuries have a variety of pathologies, including intervertebral disk disease, fractures, and luxations (dislocations) of the vertebral column. Although considerable controversy exists over the most appropriate way to manage acute spinal cord injuries, early surgical intervention or decompression remains the best treatment option in managing acute compressive injuries in veterinary patients. High-dose methylprednisolone sodium succinate, an established treatment in human medicine, is falling out of favor because studies have shown little therapeutuc benefit and severe adverse effects.
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