Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

Mechanical Ventilation I: Indication and Settings

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Pneumonia V: Nursing management and Prevention

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.

Pneumonia III: Complications and Assessment

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Antipsychotics and the QTc Interval During Delirium in the Intensive Care Unit: A Secondary Analysis of a Randomized Clinical Trial.

JAMA network open·2024

Same author

Data-derived subtypes of delirium during critical illness.

EBioMedicine·2024

Same author

Comparison of SAT and SBT Conduct During the ABC Trial and PILOT Trial.

Journal of intensive care medicine·2023

Same author

Discussions on VT4COVID.

The Lancet. Respiratory medicine·2023

Same author

Holistic care in healthy aging: Caring for the wholly and holy human.

Aging cell·2023

Same author

Modifiable in-hospital factors for 12-month global cognition, post-traumatic stress disorder symptoms, and depression symptoms in adults hospitalized with COVID-19.

Influenza and other respiratory viruses·2023

Search research articles

Related Experiment Video

Updated: Jun 28, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

Evidence-based algorithms for diagnosing and treating ventilator-associated pneumonia.

Richard J Wall¹, E Wesley Ely, Thomas R Talbot

¹Pulmonary, Critical Care and Sleep Disorders Medicine, Southlake Clinic, Valley Medical Center, Renton, Washington 98055, USA. brickw@u.washington.edu

Journal of Hospital Medicine

|October 28, 2008

Summary

Ventilator-associated pneumonia (VAP) diagnosis and management algorithms were developed for mechanically ventilated patients. These practical, evidence-based tools offer standardized guidance for clinicians in intensive care units (ICUs).

Related Experiment Videos

Last Updated: Jun 28, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia

Published on: June 28, 2018

Area of Science:

Critical Care Medicine
Infectious Diseases
Hospital Administration

Background:

Ventilator-associated pneumonia (VAP) is a significant complication in intensive care units (ICUs), leading to increased morbidity and healthcare costs.
Current diagnostic and management strategies for VAP in mechanically ventilated patients remain uncertain due to patient heterogeneity.
The need for standardized, evidence-based approaches to VAP is critical for improving patient outcomes.

Purpose of the Study:

To develop practical algorithms for the diagnosis and treatment of VAP in mechanically ventilated patients.
To review current evidence and establish consensus-based guidelines for VAP management.
To illustrate the application of these algorithms through clinical case examples.

Main Methods:

A descriptive study utilizing data from a national collaborative focused on reducing healthcare-associated infections.
Development of algorithms by an interdisciplinary team, including infectious disease specialists, intensivists, nurses, and pharmacists.
Algorithms were iteratively refined based on published evidence and existing guidelines, including CDC VAP guidelines.

Main Results:

Practical algorithms for diagnosing and managing VAP were successfully developed.
The algorithms encompass diagnostic and treatment strategies for infant, pediatric, immunocompromised, and adult ICU patients.
An interdisciplinary team approach facilitated the consensus-driven development of these tools.

Conclusions:

The developed algorithms provide a standardized, evidence-based approach to VAP diagnosis and management.
These algorithms offer real-time guidance for clinicians facing complex VAP cases in ICUs.
Implementation of these algorithms can potentially improve the consistency and effectiveness of VAP care.