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Updated: Jun 28, 2026

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Published on: May 1, 2020
Prevention and curative management of hypertrophic scar formation
Monica C T Bloemen1, Willem M van der Veer, Magda M W Ulrich
1Association of Dutch Burn Centers, Beverwijk, The Netherlands.
Abstract:
Although hypertrophic scarring commonly occurs following burns, many aspects such as incidence of and optimal treatment for scar hypertrophy remain unclear. This review will focus on hypertrophic scar formation after burn in particular, exploring multiple treatment options and describing their properties as well as effectiveness. To evaluate treatment efficacy and scar development, clinical scar assessment is of eminent importance. Furthermore, recommendations regarding the classification of hypertrophy in the daily practice and in clinical trials are implemented.
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