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Mutational analysis and a structural model of methyl-directed restriction enzyme Mrr

Jerzy Orlowski1, Mehari Tesfazgi Mebrhatu, Chris W Michiels

  • 1Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, Ul. Ks. Trojdena 4, 02-109 Warsaw, Poland.

Biochemical and Biophysical Research Communications
|October 28, 2008
PubMed
Summary

High pressure stress activates the Mrr protein, a Type IV restriction enzyme in Escherichia coli. This study analyzed Mrr mutants under pressure, revealing insights into enzyme structure and function.

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