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Updated: Jun 28, 2026
Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
Published on: March 6, 2018
Holmium laser enucleation of prostate in patients with prostate size </=60 cm3
Ehab A Elzayat1, Ismail Khalaf, Mohamed Elgallad
1Division of Urology, McGill University, Montreal, Quebec, Canada; Department of Urology, Al-Azhar University, Cairo, Egypt.
Objectives:
To evaluate the safety and efficacy of holmium laser enucleation of the prostate in patients with small to moderate size prostate.
Methods:
We retrospectively reviewed the data of 224 patients with a preoperative prostate size
Results:
The mean prostate size was 43 +/- 11.1 cm(3), the mean operative time was 80 minutes, and the enucleated tissue weight was 24 g. The mean catheterization time and hospital stay was 1.2 and 1.4 days, respectively. No major intraoperative complications were encountered. Only 2 patients (0.9%), who were receiving anticoagulation therapy, required a postoperative blood transfusion. At 1 year postoperatively, the International Prostate Symptom Score had improved from 17.6 +/- 6.7 to 4.9 +/- 4.4 (72%), the quality-of-life score had improved from 3.5 +/- 1.3 to 1.2 +/- 1.3 (66%), the peak urinary flow rate had increased from 7.5 +/- 3.1 to 21.2 +/- 9.5 mL/s (183%), and the postvoid residual urine volume had decreased from 155 +/- 170 to 27 +/- 48 mL (83%).
Conclusions:
Holmium laser enucleation of the prostate is safe and effective treatment in patients with small to moderate size prostate as well as those with larger prostates, with low morbidity and a short catheterization time and hospital stay.
