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Mouthwash and oral cancer risk: an update
1Istituto di Ricerche Farmacologiche Mario Negri Milano e Istituto di Statistica Medica e Biometria G.A. Maccacaro, Università degli Studi di Milano, Milano, Italy. lavecchia@marionegri.it
Abstract:
The possible relationship between mouthwash use and oral cancer risk has been the subject of at least 10 case-control studies published over the last three decades. Three of these reported relative risks above unity and seven no consistent association. Only a few studies, moreover, included information on different types of mouthwash, and addressed the issue of alcohol-containing mouthwash. Thus, critical review of published data revealed that a link between mouthwash use, specifically alcohol-containing mouthwash, and oral cancers is not supported by epidemiological evidence.
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