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Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
Practical considerations for multiple myeloma: an overview of recent data and current options
1Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA. sloni01@emory.edu
Clinical Lymphoma & Myeloma
|November 1, 2008
Summary
Novel agents significantly improve treatment outcomes for multiple myeloma (MM). Promising combinations are now used in induction therapy, showing impressive responses and potential survival benefits.
Area of Science:
- Hematology
- Oncology
- Pharmacology
Background:
- Multiple myeloma (MM) treatment landscape has evolved with novel agents.
- These agents demonstrate improved response rates and survival benefits in MM.
Purpose of the Study:
- To review promising novel agent combinations for MM induction therapy.
- To discuss emerging agents for relapsed MM.
Main Methods:
- Literature review of novel agents in multiple myeloma.
- Analysis of data on induction and relapsed/refractory MM treatment.
Main Results:
- Novel agents show impressive responses in MM induction therapy.
- Bortezomib and lenalidomide are effective in relapsed/refractory MM and induction settings.
Conclusions:
- Novel agent combinations represent a significant advancement in MM induction therapy.
- Ongoing research into new agents holds promise for relapsed MM.
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