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Updated: Jun 28, 2026

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc

Published on: April 30, 2010

FlyEx, the quantitative atlas on segmentation gene expression at cellular resolution.

Andrei Pisarev¹, Ekaterina Poustelnikova, Maria Samsonova

¹Department of Computational Biology, St. Petersburg State Polytechnical University, St. Petersburg 195251, Russia.

Nucleic Acids Research

|October 28, 2008

Summary

The FlyEx database provides access to Drosophila segmentation gene expression data, enabling analysis of gene pattern dynamics and variability. This resource facilitates research into early developmental gene function.

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Area of Science:

Developmental Biology
Genomics
Bioinformatics

Background:

Gene expression datasets offer insights into organismal functional states.
Large datasets on segmentation gene expression in Drosophila blastoderm have been acquired.

Purpose of the Study:

To develop an efficient data access system for Drosophila segmentation gene expression.
To enable analysis of gene expression dynamics and pattern variability.

Main Methods:

Development of the FlyEx database (http://urchin.spbcas.ru/flyex).
Curated 4716 images from 1579 embryos, encompassing 14 segmentation genes and 9,500,000 quantitative records.
Provided reference data for segmentation genes across developmental cycles 11-13 and cycle 14A.

Related Experiment Videos

Last Updated: Jun 28, 2026

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc

Laser Microdissection Applied to Gene Expression Profiling of Subset of Cells from the Drosophila Wing Disc

Published on: April 30, 2010

Main Results:

FlyEx database offers comprehensive data on segmentation gene expression patterns.
Supports analysis of gene expression domain formation dynamics (1.5 h of development).
Enables data quality examination and variability estimation.

Conclusions:

The FlyEx database serves as a valuable resource for studying Drosophila development.
Facilitates monitoring and analysis of segmentation gene expression dynamics.
Supports data downloads and custom reference dataset creation for enhanced analysis.