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Updated: Jun 28, 2026
13:19
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Dietary habits and prostate cancer detection: a case-control study
Moamen Amin1, Suganthiny Jeyaganth, Nader Fahmy
1Division of Urology, Department of Surgery, McGill University Health Centre, Montréal, Que.
Summary
A diet high in meat, such as red meat and sausages, is linked to a nearly 3-fold increased risk of prostate cancer. Conversely, consuming fish may lower the risk of prostate cancer detection.
Area of Science:
- Urology
- Nutritional Science
- Oncology
Background:
- Nutritional factors are increasingly recognized for their potential role in prostate cancer development.
- Understanding the link between dietary habits and prostate cancer risk is crucial for prevention strategies.
Purpose of the Study:
- To investigate the association between specific dietary patterns and the detection of prostate cancer.
- To explore the relationship between diet and prostate cancer aggressiveness.
Main Methods:
- A cohort of 917 patients undergoing prostate biopsy due to elevated or rising prostate-specific antigen (PSA) or abnormal digital rectal examination was studied.
- Dietary habits were assessed using a self-administered food frequency questionnaire prior to biopsy results.
- Univariable and multivariable logistic regression analyses were performed to identify predictors of prostate cancer and its aggressiveness.
Main Results:
- Prostate cancer was detected in 42% of the study participants.
- A diet rich in meat products (red meat, ham, sausages) was significantly associated with an increased risk of prostate cancer (OR 2.91, p=0.027).
- A fish-inclusive diet showed a reduced risk of prostate cancer detection (OR 0.54, p=0.017), but no dietary components were linked to cancer aggressiveness.
Conclusions:
- Dietary habits, particularly meat and fish consumption, show a significant association with prostate cancer detection.
- Meat consumption appears to elevate prostate cancer risk, while fish consumption may offer a protective effect.
- These findings contribute to the growing evidence base supporting a connection between diet and prostate cancer risk.
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