[Polyneuropathy in uremic patients in chronic hemodialysis (clinico-morphologic findings]

Among 50 patients who suffered from chronic renal insufficiency and who were on a chronic hemodialysis, 25 demonstrated uremic polyneuropathy with a different degree of expressiveness which depended upon the duration azotemia. A histological study of 13 postmortem cases detected a microfocal demyelinization in the peripheral nerves, and in cases of expressed pathology there were changes in the axon cast of the peripheral nerves and neurogenic muscular atrophy. There were no direct correlations between the development of polyneuropathy and the amount of hemodialysis sessions.