Related Experiment Video

Updated: Jun 28, 2026

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
06:04

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

[Relationship between pulse wave velocity and the NYha classification of coronary insufficiency]

Wei-Ping Sun1, Yong-Quan Wu, Jue Li

  • 1Department of Cardiology, Tongji Hospital of Tongji University, Shanghai 200065, China.

Zhonghua Nei Ke Za Zhi
|October 29, 2008
PubMed

Insights

Brachial-ankle pulse wave velocity (baPWV) correlates with heart failure stages. Elevated baPWV may help diagnose early cardiac dysfunction in patients with coronary heart disease.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Biomedical Engineering

Background:

  • Coronary atherosclerotic heart disease (CAD) is a leading cause of morbidity and mortality.
  • Assessing cardiac dysfunction is crucial for managing heart failure.
  • Early detection of cardiac dysfunction can improve patient outcomes.

Purpose of the Study:

  • To investigate the relationship between brachial-ankle pulse wave velocity (baPWV) and cardiac dysfunction.
  • To evaluate baPWV as a potential biomarker for early-stage cardiac dysfunction.

Main Methods:

  • 253 patients with CAD were classified using the New York Heart Association (NYHA) functional classification.
  • Brachial-ankle pulse wave velocity (baPWV) was measured non-invasively.
  • Biomarkers including BNP, ejection fraction (EF), left ventricular end-diastolic volume (LVEDV), and left ventricular end-systolic volume (LVESV) were assessed.

Main Results:

  • baPWV showed significant correlation with NYHA classification (r = 0.444, P < 0.001) and BNP levels (r = 0.394, P < 0.001).
  • A significant inverse correlation was observed between baPWV and left ventricular end-diastolic volume (r = -0.130, P < 0.05).
  • Receiver operating characteristic (ROC) curve analysis indicated baPWV thresholds for diagnosing mild cardiac dysfunction (≥1717 cm/s) and moderate dysfunction (≥1900 cm/s) with varying sensitivity and specificity.

Conclusions:

  • Brachial-ankle pulse wave velocity (baPWV) is significantly correlated with the NYHA classification of heart failure.
  • baPWV may serve as a prospective index for diagnosing early-stage cardiac dysfunction in patients with CAD.
Abstract

More Related Videos

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging06:08

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

Published on: February 7, 2014

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness05:51

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

Published on: May 3, 2018

Related Concept Videos

Pulse amplitude and quality01:17

Pulse amplitude and quality

Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
Pulse01:16

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
Pulse01:05

Pulse

The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...