Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asepsis01:28

Asepsis

The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
Acute Inflammation III: Local and Systemic Effects01:25

Acute Inflammation III: Local and Systemic Effects

Acute inflammation produces a coordinated set of local and systemic changes that limit injury, eliminate pathogens, and initiate repair. These responses arise within minutes of infection, trauma, or chemical insult and are driven by vascular alterations and leukocyte-derived mediators. When the stimulus resolves, the reaction typically abates within days.Local EffectsAt the site of injury, arteriolar vasodilation increases blood flow, resulting in redness and warmth. Simultaneously, increased...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A liberal strategy of red blood cell transfusion reduces cardiogenic shock in elderly patients undergoing cardiac surgery.

The Journal of thoracic and cardiovascular surgery·2015
Same author

A new device for the prevention of pulmonary embolism in critically ill patients: Results of the European Angel Catheter Registry.

The journal of trauma and acute care surgery·2015
Same author

A randomized, placebo-controlled trial of preemptive antifungal therapy for the prevention of invasive candidiasis following gastrointestinal surgery for intra-abdominal infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2015
Same author

Near infrared spectroscopy (NIRS) to assess the effects of local ischemic preconditioning in the muscle of healthy volunteers and critically ill patients.

Microvascular research·2015
Same author

Should red cell transfusion be individualized? Yes.

Intensive care medicine·2015
Same author

Assessing Cellular Responses in Sepsis.

EBioMedicine·2015

Related Experiment Video

Updated: Jun 28, 2026

A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

Defining sepsis.

Jean-Louis Vincent1, Hakan Atalan Korkut

  • 1Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, 808, Route de Lennik, 1070 Brussels, Belgium. jlvincen@ulb.ac.be

Clinics in Chest Medicine
|October 29, 2008
PubMed
Summary
This summary is machine-generated.

Accurate definitions of sepsis are crucial for patient diagnosis, treatment, and research. While recent consensus offers global definitions, further characterization of the sepsis response is needed for better interventions and reduced mortality.

More Related Videos

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

Related Experiment Videos

Last Updated: Jun 28, 2026

A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats
05:56

A Reproducible Intensive Care Unit-Oriented Endotoxin Model in Rats

Published on: February 20, 2021

Area of Science:

  • Medical definitions
  • Sepsis research
  • Infectious disease

Background:

  • Definitions are vital for medical diagnosis, treatment, and research clarity.
  • Sepsis, the host response to infection, presents complex challenges for precise definition.
  • Existing definitions of sepsis and infection require further refinement.

Purpose of the Study:

  • To highlight the importance of clear medical definitions.
  • To discuss the challenges in defining sepsis.
  • To emphasize the need for improved sepsis characterization.

Main Methods:

  • Literature review on medical definitions.
  • Analysis of sepsis complexity and patient groups.
  • Discussion of recent consensus on sepsis and infection definitions.

Main Results:

  • Definitions are critical at both patient and research levels.
  • Complexity of sepsis response hinders definitive classification.
  • Recent consensus provides foundational definitions.

Conclusions:

  • Further work is essential to fully characterize sepsis response in patients.
  • Improved characterization will enable better targeting of new interventions.
  • The ultimate goal is to decrease high sepsis-related mortality rates.