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Related Experiment Video

Updated: Jun 28, 2026

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

New biologic agents and immunologic strategies.

Rebecca L Elstrom¹, Peter Martin, John P Leonard

¹Division of Hematology/Oncology, Weill Cornell Medical College, 520 East 70th Street, Starr 340, New York, NY 10021, USA.

Hematology/Oncology Clinics of North America

|October 29, 2008

Summary

Traditional chemotherapy for non-Hodgkin lymphoma offers remissions but not always long-term survival. Newer immunotherapies, like monoclonal antibodies, are improving treatment by harnessing the immune system to target cancer cells.

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Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo

Published on: January 7, 2019

Area of Science:

Oncology
Immunology

Background:

Non-Hodgkin lymphoma treatment historically relies on chemotherapy, achieving remissions but limited long-term disease-free survival.
Recent advances leverage a deeper understanding of tumor biology and host interactions for novel therapeutic strategies.

Purpose of the Study:

To review the evolution of non-Hodgkin lymphoma therapies.
To highlight the role of immunotherapies, particularly monoclonal antibodies, in targeting cancer.

Main Methods:

Review of therapeutic advancements in non-Hodgkin lymphoma treatment over the past two decades.
Focus on biologic understanding and immune-based mechanisms.

Main Results:

Monoclonal antibodies represent a significant advancement in lymphoma treatment.
Emerging novel therapeutics show promise for further improving patient outcomes.

Conclusions:

The development of immunotherapies, including monoclonal antibodies, has transformed non-Hodgkin lymphoma treatment.
Ongoing research into novel agents and immune-optimizing strategies is expected to enhance antitumor activity and patient survival.