Related Experiment Videos
Predicting need for hospitalization in acute pediatric asthma
Marc Gorelick1, Philip V Scribano, Martha W Stevens
1Department of Pediatrics, Medical College of Wisconsin and Children's Research Institute, Milwaukee, WI, USA. mgorelic@mcw.edu
Insights
A simple clinical model accurately predicts successful emergency department discharge for children with acute asthma. However, predicting the need for extended care or inpatient admission remains challenging.
Area of Science:
- Pediatric Emergency Medicine
- Respiratory Medicine
- Clinical Decision Support
Background:
- Acute asthma is a common reason for pediatric emergency department (ED) visits.
- Accurate disposition decisions are crucial for optimizing patient care and resource allocation.
Purpose of the Study:
- To develop and validate predictive models for determining hospitalization needs in children with acute asthma treated in the ED.
- To improve disposition decisions for pediatric asthma patients.
Main Methods:
- Prospective cohort study involving children aged 2+ years treated for acute asthma in two pediatric EDs.
- Development of predictive models using logistic regression and recursive partitioning with historical and clinical data.
- Validation of models in an independent ED cohort.
Main Results:
- A model incorporating the Pediatric Asthma Severity Score and albuterol treatments accurately predicted successful ED discharge (AUC 0.89-0.92).
- A classification tree using ED treatment data, clinical score, and pulse oximetry showed moderate accuracy (62-63%) in predicting short-stay vs. inpatient care.
Conclusions:
- A straightforward clinical model can reliably predict which children with acute asthma can be safely discharged from the ED.
- Predicting the specific disposition (short-stay vs. inpatient) for children requiring extended care presents a significant challenge.
Objectives:
To develop and validate predictive models to determine the need for hospitalization in children treated for acute asthma in the emergency department (ED).
Methods:
Prospective cohort study of children aged 2 years and older treated at 2 pediatric EDs for acute asthma. The primary outcome was successful ED discharge, defined as actual discharge from the ED and no readmission for asthma within 7 days, versus need for extended care. Among those defined as requiring extended care, a secondary outcome of inpatient care (>24 hours) or short-stay care (<24 hours) was defined. Logistic regression and recursive partitioning were used to create predictive models based on historical and clinical data from the ED visit. Models were developed with data from 1 ED and validated in the other.
Results:
There were 852 subjects in the derivation group and 369 in the validation group. A model including clinical score (Pediatric Asthma Severity Score) and number of albuterol treatments in the ED distinguished successful discharge from need for extended care with an area under the receiver-operator characteristic curve of 0.89 (95% confidence interval [CI], 0.87-0.92) in the derivation group and 0.92 (95% CI, 0.89-0.95) in the validation group. Using a score of 5 or more as a cutoff, the likelihood ratio positive was 5.2 (95% CI, 4.2-6.5), and the likelihood ratio negative was 0.22 (95% CI, 0.17-0.28). Among those predicted to need extended care, a classification tree using number of treatments in the ED, clinical score at end of ED treatment, and initial pulse oximetry correctly classified 63% (95% CI, 56-70) of the derivation group as short stay or inpatient, and 62% (95% CI, 55-68) of the validation group.
Conclusions:
Successful discharge from the ED for children with acute asthma can be predicted accurately using a simple clinical model, potentially improving disposition decisions. However, predicting correct placement of patients requiring extended care is problematic.
Related Concept Videos
Asthma-IV: Nursing Management
First, in...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma III: Clinical Manifestations
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma I: Introduction