Advances in recovery of novel biocatalysts from metagenomes
Related Experiment Video
Updated: Jun 28, 2026

Immobilization of Multi-biocatalysts in Alginate Beads for Cofactor Regeneration and Improved Reusability
Published on: April 22, 2016
Helen L Steele1, Karl-Erich Jaeger, Rolf Daniel
1Biozentrum Klein Flottbek, Abteilung für Mikrobiologie & Biotechnologie, Universität Hamburg, Hamburg, Germany.
Abstract:
Metagenomics has accelerated the process of discovery of novel biocatalysts by enabling scientists to tap directly into the entire diversity of enzymes held within natural microbial populations. Their characterization has revealed a great deal of valuable information about enzymatic activity in terms of factors which influence their stability and activity under a wide range of conditions. Many of the biocatalysts have particular properties making them suitable for biotechnological applications. A diverse array of strategies has been developed to optimize each step of the process of generating and screening metagenomic libraries for novel biocatalysts. This review covers the diversity of metagenome-derived enzymes characterized to date, and the strategies currently being developed to optimize discovery of novel metagenomic biocatalysts.
Related Concept Videos
Bioreactor Controls-III
Bioremediation
Microbial Bioremediation of Hydrocarbons
Microbial Bioremediation of Plastics
Modern Molecular Taxonomy
Amino Acid Catabolism

