Substoichiometric masking-I General considerations and quantitative treatment
1School of Chemistry, Georgia Institute of Technology, Atlanta, Ga, 30332, U.S.A.
Talanta
|July 1, 1968
Summary
Substoichiometric masking uses less masking agent than normally required. This method effectively reduces interfering substances below critical levels, proving advantageous when excess agents interfere with results.
Area of Science:
- Analytical Chemistry
- Chemical Analysis Techniques
Background:
- Interference from substances can compromise analytical results.
- Traditional masking methods sometimes use excess agents, negatively impacting the target analyte.
Purpose of the Study:
- Introduce and evaluate substoichiometric masking.
- Provide a method to assess the feasibility of this technique.
Main Methods:
- Implementing masking agent addition below stoichiometric equivalence.
- Deriving mathematical formulae to assess feasibility.
Main Results:
- Demonstrated that substoichiometric masking reduces free interfering substances below the interference threshold.
- Showcased the technique's utility when excess masking agents are detrimental.
Conclusions:
- Substoichiometric masking is a viable strategy for mitigating interference.
- The derived formulae offer a quantitative approach to evaluating its application.
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