Related Experiment Video
Updated: Jul 30, 2026

05:05
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
A new contact neodymium:YAG laser for cyclophotocoagulation
A G Iwach1, M V Drake, H D Hoskins
1Foundation for Glaucoma Research, San Francisco, Calif 94102.
Summary
A new Neodymium:YAG laser effectively treats rabbit eyes, causing ciliary body disruption with minimal scleral damage. This laser technology shows promise for ophthalmic procedures like cyclophotocoagulation.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Laser Technology
Background:
- Glaucoma treatment often involves reducing intraocular pressure.
- Cyclophotocoagulation and cyclodiathermy are established methods to achieve this by targeting the ciliary body.
- Novel laser systems are needed for improved efficacy and safety in these procedures.
Purpose of the Study:
- To evaluate a new compact Neodymium:YAG laser system for ocular cyclodestruction.
- To assess the efficacy and safety of this laser in a rabbit model.
Main Methods:
- A novel compact Neodymium:YAG laser (40 kg) was developed, delivering 1.0 ms pulses (100-800 mJ/pulse) via a 320-micron fiber optic probe.
- Cyclophotocoagulation was performed on five rabbit eyes using 1-3 pulses/exposure.
- Transscleral cyclodiathermy was also performed in rabbits.
Main Results:
- Histopathology confirmed ciliary body disruption and hemorrhage in treated eyes.
- No damage to the overlying sclera was observed.
- Transscleral application resulted in significant ciliary body disruption with minimal scleral injury.
Conclusions:
- The developed Neodymium:YAG laser system is effective in causing ciliary body disruption.
- The laser demonstrates a favorable safety profile with minimal scleral damage in a rabbit model.
- This technology holds potential for ophthalmic applications requiring ciliary body treatment.

