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Related Concept Videos

Titration of Polyprotic Acids with a Strong Base01:23

Titration of Polyprotic Acids with a Strong Base

Titration of a polyprotic acid, which contains multiple ionizable protons, involves distinct dissociation steps, each with its own dissociation constant (Ka). Each successive Ka is weaker than the previous one. In the titration of a polyprotic acid like sulfurous acid with a strong base such as sodium hydroxide, the base first neutralizes the initial ionizable proton, forming an intermediate species (e.g., hydrogen sulfite ions). This step's titration curve resembles that of a weak monoprotic...
Titration of a Polyprotic Acid02:08

Titration of a Polyprotic Acid

A polyprotic acid contains more than one ionizable hydrogen and undergoes a stepwise ionization process. If the acid dissociation constants of the ionizable protons differ sufficiently from each other, then the titration curve for such polyprotic acid generates a distinct equivalence point for each of its ionizable hydrogens. Therefore, titration of a diprotic acid results in the formation of two equivalence points, whereas the titration of a triprotic acid results in the formation of three...
Titration of a Weak Acid with a Strong Base01:30

Titration of a Weak Acid with a Strong Base

In titrating a weak acid with a strong base, different calculation methods are applied at various stages. Initially, the pH of a weak acid like acetic acid is calculated using its dissociation constant (Ka) and an ICE table. Upon addition of a strong base such as sodium hydroxide, a buffer forms, and its pH is determined using the Henderson-Hasselbalch equation. As more base is added and the titration reaches the halfway point, the pH becomes equal to the pKa of the acid, indicating equal...
Solution Composition During Acid/Base Titrations01:17

Solution Composition During Acid/Base Titrations

The titration of a weak acid with a strong base results in the formation of water and the conjugate base of the acid. For instance, titrating acetic acid with sodium hydroxide leads to the formation of water and sodium acetate. A solution of acetic acid and sodium acetate constitutes a buffer whose relative concentration at different stages of the titration is indicated by the α values, which represent percentages of the weak acid and its conjugate base.
The α0 and α1 values represent the...
Acid–Base Titration: Overview01:26

Acid–Base Titration: Overview

An acid-base titration is a technique used to determine the concentration of an unknown acid or base, using a titrant of known concentration–either a base for acid titration or an acid for base titration. The process involves gradually adding the titrant, leading to a predictable change in the pH of the solution. This change is plotted on a titration curve, showing how a solution's pH varies with the amount of titrant added. Such curves are instrumental in monitoring the titration's progress...
Titration of Polyprotic Base with a Strong Acid01:18

Titration of Polyprotic Base with a Strong Acid

The titration of a polyprotic base such as sodium carbonate with a strong acid such as hydrochloric acid results in two equivalence points on the titration curve. At the first equivalence point, the carbonate ions in the base are completely converted to bicarbonate ions. The second equivalence point corresponds to the complete conversion of bicarbonate ions to carbonic acid, which dissociates into carbon dioxide and water. The region before the first equivalence point corresponds to the...

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Related Experiment Video

Updated: Jun 28, 2026

Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method
08:21

Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method

Published on: May 18, 2018

Titration of phytic acid.

R J Reeves1, R T Carroll, G P Gennaro

  • 1Diagnostic Isotopes Incorporated, Bloomfield, NJ 07003, U.S.A.

Talanta
|November 1, 1979
PubMed
Summary

Titrimetric assays for phytic acid were developed using iron(III) or thorium titration. Stannous chloride causes errors, but phytic acid

Area of Science:

  • Analytical Chemistry
  • Biochemistry

Background:

  • Phytic acid is a key phosphorus storage compound in plants.
  • Accurate quantification of phytic acid is crucial for nutritional and industrial applications.

Purpose of the Study:

  • To describe titrimetric methods for phytic acid determination.
  • To investigate potential interferences and characterize the complex formed.

Main Methods:

  • Titration of phytic acid with iron(III) and thorium solutions.
  • Analysis of interference from stannous chloride.
  • Determination of the stoichiometry of the thorium-phytate complex.

Main Results:

  • Established titrimetric assays for phytic acid using iron(III) and thorium.

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Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors
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Preparation of Quality Inositol Pyrophosphates
10:34

Preparation of Quality Inositol Pyrophosphates

Published on: September 3, 2011

Related Experiment Videos

Last Updated: Jun 28, 2026

Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method
08:21

Optimized Procedure for Determining the Adsorption of Phosphonates onto Granular Ferric Hydroxide using a Miniaturized Phosphorus Determination Method

Published on: May 18, 2018

Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors
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Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors

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Preparation of Quality Inositol Pyrophosphates
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Preparation of Quality Inositol Pyrophosphates

Published on: September 3, 2011

  • Identified stannous chloride as a significant interfering agent, causing proportional negative errors.
  • Determined a thorium:phytate molar ratio of 2:1 in the formed complex.
  • Conclusions:

    • The developed titrimetric methods provide a means for phytic acid quantification.
    • Understanding stannous chloride interference is essential for accurate results.
    • The 2:1 thorium:phytate ratio suggests phytic acid possesses two chelating centers.