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NMR assay of ephedrine hydrochloride in tablets
M M Hassan1, M U Zubair, J S Mossa
1Departments of Pharmaceutical Chemistry and Pharmacognosy, College of Pharmacy, Riyad University, Riyad, Saudi Arabia.
Abstract:
A rapid NMR method is described for the determination of ephedrine hydrochloride. The relative standard deviations are 1.5% and 1.2% for the pure drug and tablets respectively. The results for synthetic mixtures and tablets are comparable to those obtained by the B.P. 1973 method. In addition, the NMR spectrum furnishes a specific means of identification of ephedrine.
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