Related Experiment Video
Updated: Jun 28, 2026

Titration ELISA as a Method to Determine the Dissociation Constant of Receptor Ligand Interaction
Published on: February 15, 2018
A desk-computer program for calculation of the parameters of acid-base titration curves and protonation or
1Department of Chemistry, College of Food Technology, Hódmezövásárhely, POB 79 and Gy. Juhász Teacher's Training College, Szeged, Hungary.
Abstract:
The program MINIPOT is designed to run on a desk-computer with 16-kbyte of memory. It can calculate the optimum values of the parameters of a blank acid-base titration in any solvent, and the protonation/deprotonation or overall stability constants of a maximum of four species with compositions H(q)L(p) or M(q)L(p) from potential, titrant volume and analytical concentration data. The program, written in BASIC, is based on the least-squares principle and is capable of simultaneous refinement of a maximum of four parameters.
Related Concept Videos
Potentiometric Titration: Overview
Acid-Base Titration Curves
For a titration carried out for 25.00 mL of 0.100...
Conductometric Titrations: Strong Acid-Base and Weak Acid-Base Titrations
Acid–Base Titration: Overview
Titration of a Weak Acid with a Strong Base
Titration Calculations: Weak Acid - Strong Base
For the titration of 25.00 mL of 0.100 M CH3CO2H with 0.100 M NaOH, the reaction can be represented as:

