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A Computer-assisted Multi-electrode Patch-clamp System
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Computer control of microprocessor-based instruments by keypad emulation.

P M Wiegand1, S R Crouch

  • 1Department of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322, U.S.A.

Talanta
|January 1, 1985
PubMed
Summary
This summary is machine-generated.

A novel keypad emulation method allows laboratory microcomputers to control microprocessor-based instruments. This approach enables automated experimental sequencing and data processing for enhanced laboratory workflows.

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Area of Science:

  • Analytical Chemistry
  • Instrumentation
  • Laboratory Automation

Background:

  • Microprocessor-based instruments often rely on manual keypad input for operation.
  • Controlling these instruments via laboratory computers can improve experimental reproducibility and efficiency.
  • Existing methods may lack flexibility in integrating diverse laboratory equipment.

Purpose of the Study:

  • To present a keypad emulation method for controlling microprocessor-based instruments using laboratory microcomputers.
  • To demonstrate the method's applicability to instruments with polled keypad arrays.
  • To showcase the potential for seamless integration and automated experimental control.

Main Methods:

  • Developed a keypad emulation technique to interface laboratory microcomputers with microprocessor-based instruments.
  • Implemented the method to control a microprocessor-based High-Performance Liquid Chromatography (HPLC) solvent-delivery system.
  • Utilized the laboratory microcomputer to synchronize and sequence all aspects of the HPLC experiment.

Main Results:

  • Successfully demonstrated control of an HPLC solvent-delivery system via a laboratory microcomputer.
  • Enabled automated sequencing of solvent delivery, valve control (column switching, back-flushing), data acquisition, and data processing.
  • Validated the keypad emulation method for flexible instrument control.

Conclusions:

  • The keypad emulation method provides a versatile solution for automating laboratory instruments.
  • This approach enhances laboratory efficiency by enabling synchronized and sequenced experimental control.
  • The technique is applicable to a wide range of polled keypad array instruments, facilitating greater laboratory automation.