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Spectrophotometric and fluorimetric determination of nomifensine maleate
A A Wahbi1, M A Abounassif, El-R A Gad-Kariem
1Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh-11451, Saudi Arabia.
Abstract:
Three methods have been developed for the determination of nomifensine maleate alone and in capsules: a spectrophotometric, an iodine charge-transfer, and a spectrofluorimetric method. All three give linear calibration graphs, over the ranges 20-100, 1-5 and 0.1-0.5 microg/ml, respectively, with coefficients of variation of 0.8, 1.3 and 1.3%, respectively.
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