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Updated: Jun 28, 2026

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
Published on: February 23, 2017
Use of an ion-selective membrane electrode for the determination of the active components in intestopan
M S Ionescu1, M Lazarescu, A Ionescu
1Institute of Chemical and Pharmaceutical Research, 74351-Sos. Vitan 112, Bucharest-3, Romania.
Abstract:
The conditions for the determination of broxyquinoline and brobenzoxaldine, the active components of "Intestopan", by use of ion-selective membrane electrodes are described. Broxyquinoline is determined directly through precipitation with CuSO(4), and brobenzoxaldine is first hydrolysed in alkaline solution and the product precipitated with CuSO(4). In both cases the CuSO(4) in excess is determined by potentiometric titration at pH 5.6 with EDTA, a Cu(2+)-selective electrode being used for end-point detection.
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