Simultaneous spectrophotometric determination of furazolidone and berberine in tablet form

Two spectrophotometric procedures are suggested for the analysis of mixtures of furazolidone and berberine in tablets. No preliminary separation step is required. The first procedure is based on the use of the modified Vierordt equation as developed by Glenn. The second depends on the spectral changes induced for both components by reduction with zinc and hydrochloric acid. The methods have been applied to the assay of mixtures of the two compounds in tablets and the results obtained compared favourably with those obtained by other methods, but the proposed methods are more accurate and precise and less time-consuming.