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Updated: Jun 28, 2026
Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
HPLC determination of niridazole
N A El-Rabbat1, H H Farag, M E El-Kommos
1Pharmaceutical Chemistry Department, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Abstract:
A high-performance liquid chromatographic method has been developed for the determination of niridazole in bulk form and in pharmaceutical dosage form. A reversed-phase system, based on an octadecylsilane-bonded stationary phase and a 60:40 v/v methanol/water mobile phase, is used. The detector response at 370 nm is linearly related to the amount injected, over a wide range. The method is sensitive, simple, rapid and precise.
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