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Updated: Jun 28, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
Analytical characterization of some pyrazolones and their copolymers with some vinyl compounds
E Ivanova1, O Todorova, A Terebenina
1Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, BG-1040 Sofia, Bulgaria.
Abstract:
Some new pyrazolones have been synthesized and their copolymers with styrene, methylmethacrylate and methacrylic acid prepared. The pyrazolones and their styrene and methylmethacrylate copolymers are insoluble in water but form chelate complexes with some alkaline-earth and transition metal ions. The water-soluble methacrylic acid copolymers do not form complexes with these elements, however, probably because of hydrogen-bonding of the chelating groups to the methacrylic acid carboxyl groups. Special attention was paid to the complexation of Au(III), which was assumed to proceed mainly through the nitrogen atoms of the pyrazolone ring.
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