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Determination of sulpha-drugs with a piezoelectric sensor
1New Material Research Institute, Department of Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.
Abstract:
A piezoelectric sensor is used for the determination of sulpha-drugs, as pure substances and in their dosage forms, by an indirect micro method based on reaction of the sulpha-drug with bromine and reduction of the resultant N-bromoderivative with iodide to form iodine, which after extraction is monitored with a piezoelectric quartz sensor. The response of the sensor is linear from 2 x 10(-5) to 4 x 10(-4)M sulpha-drug.
