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Automated titrations with an alternate flow exponential speed variation system.

C N Yarnitzky¹, N Klein, O Cohen

¹Department of Chemistry, Technion, Israel Institute of Technology, Haifa, Israel 32000.

|December 1, 1993

Summary

This study introduces an automatic titration system with an alternate flow exponential speed variation. The novel twin cycle procedure enables accurate sample concentration calculation without precalibration, improving precision and eliminating tubing wear errors.

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Area of Science:

Analytical Chemistry
Instrumentation Science

Background:

Traditional automatic titration systems can suffer from inaccuracies due to tubing deterioration and require precalibration.
Developing precise and robust analytical methods is crucial for accurate chemical analysis.

Purpose of the Study:

To describe a novel alternate flow exponential speed variation system for automatic titrations.
To demonstrate a method for accurate sample concentration determination without precalibration.
To eliminate errors associated with peristaltic pump tubing wear in automated titrations.

Main Methods:

The system utilizes two peristaltic pumps and two three-way valves for fluid handling.
A twin cycle titration procedure involving forward and reverse cycles with variable pump speeds was employed.
A mixing coil and detector facilitate the titration process and measurement.

Main Results:

The system achieved an accuracy better than 0.5% for sample concentration determination.
The titration process required approximately 2 minutes and 2 ml of sample volume.
The alternate flow method effectively compensated for tubing deterioration, eliminating associated errors.

Conclusions:

The described alternate flow exponential speed variation system offers a precise and reliable method for automatic titrations.
This innovative approach negates the need for precalibration and mitigates errors from system wear.
The system demonstrates significant potential for improving efficiency and accuracy in analytical laboratories.