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Updated: Aug 27, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
[The effect of continuous positive-pressure via the nose (CPAPn) on the ventilatory pattern]
E Rodrŕiguez Becerra1, A Valera Sánchez, R Vázquez Oliva
1Servicio de Neumología, Hospital Universitario Virgen del Rocío, Sevilla.
Abstract:
The modifications in the ventilation pattern when a continuous positive pressure is applied through the nose (CPAPn) in an acute form or by increasing pressures is evaluated in 13 normal subjects and 8 individuals presenting obstructive sleep apnea syndrome (OSAS). No significant modifications are observed in breathing frequency or breathing time when 5 and 10 cm of H2 are applied. It is concluded that this mechanism does not seem to be involved in the disappearance of hypercapnia which occurs in some patients with OSAS.
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