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Related Concept Videos

Titrimetric Methods: Types and Commonly Used Strategies01:08

Titrimetric Methods: Types and Commonly Used Strategies

In chemistry, titrimetric methods are broadly classified into three types: volumetric, gravimetric, and coulometric. Volumetric titrations involve measuring the volume of a titrant of known concentration that is required to react completely with an analyte. In gravimetric titrations, the standard solution reacts with the analyte to form an insoluble precipitate, which is filtered, dried, and weighed. In coulometric titrations, current is applied to an electrochemical reaction until the reaction...
Gas Chromatography: Sample Injection Systems01:08

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Calibration Curves: Linear Least Squares01:20

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A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
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Acid-Base Titration Curves02:23

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Precipitation Titration: Overview01:26

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Isothermal Titration Calorimetry for Measuring Macromolecule-Ligand Affinity
08:45

Isothermal Titration Calorimetry for Measuring Macromolecule-Ligand Affinity

Published on: September 7, 2011

Flow injection titration-linear or logarithmic.

R Chen1, J Ruzicka, G D Christian

  • 1Center for Process Analytical Chemistry, Department of Chemistry, BG-10 University of Washington, Seattle, WA 98195, U.S.A.

Talanta
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

A new Continuous Flow Injection Titration method automates sulfuric acid and Karl Fischer titrations in oil refinery streams. This technique streamlines routine assays by integrating multiple functions within the mixing chamber and cell.

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Area of Science:

  • Analytical Chemistry
  • Chemical Engineering

Background:

  • Automating routine chemical assays in industrial settings is crucial for efficiency and accuracy.
  • Traditional titration methods can be time-consuming and labor-intensive.
  • Specific challenges exist in analyzing high sulfuric acid concentrations and performing Karl Fischer titrations in complex matrices like oil refinery streams.

Purpose of the Study:

  • To develop a simple, rapid, and automated method for assaying high sulfuric acid concentrations in oil refinery streams.
  • To develop a Coulometric Flow Injection Titration method for Karl Fischer titration in the same industrial context.
  • To explore and optimize the multifunctional role of the mixing chamber and cell within the Flow Injection Titration system.

Main Methods:

  • Development of a Continuous Flow Injection Titration (FIA) method incorporating a pretitration step for sulfuric acid analysis.
  • Implementation of a Coulometric Flow Injection Titration (FIA) method for Karl Fischer titration.
  • Investigation of the mixing chamber's functions, including pretitration dilution and viscosity reduction.
  • Utilizing the electrochemical cell as both a reaction vessel and a detector.

Main Results:

  • Successful automation of high sulfuric acid concentration assays within a narrow range.
  • Effective implementation of Coulometric FIA for Karl Fischer titration.
  • Demonstrated multifunctionality of the mixing chamber and cell, enhancing assay efficiency.
  • Validation of FIA as a powerful tool for automating routine industrial assays.

Conclusions:

  • The developed Flow Injection Titration methods offer a simple, rapid, and automated solution for critical industrial assays.
  • Integrating multiple functions into the FIA system significantly improves efficiency and reduces manual labor.
  • This approach provides a robust platform for automating routine chemical analyses in demanding environments like oil refineries.