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Published on: April 2, 2017
Effect of chemicals on glutathione peroxidase of chick liver
1Feed Safety Research Division, National Institute of Animal Health, Ibaraki, Japan.
Abstract:
Chick liver glutathione peroxidase activity was separated into selenium-dependent and selenium-independent enzyme fractions and the effects of chemicals on the activities of each fraction were examined. Clofibrate induced the selenium-dependent enzyme, while phenobarbital, butylhydroxyanisole and trans-stilbene oxide elevated selenium-independent peroxidase activity. A third enzyme, which showed glutathione peroxidase activity toward both hydrogen peroxide and cumene hydroperoxide, was found.
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