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Related Experiment Video

Updated: Jun 28, 2026

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

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Published on: April 18, 2013

Studies of the chlorpheniramine solid-state ion-selective electrode.

C L Huang, J J Ren, D F Xu

|December 1, 1996

Summary

A novel solid-state chlorpheniramine electrode was developed using a silver/silver chloride substrate. This stable electrode enables potentiometric determination of chlorpheniramine, offering a new analytical method.

Area of Science:

Electrochemistry
Analytical Chemistry
Materials Science

Background:

Development of ion-selective electrodes (ISEs) is crucial for sensitive and selective chemical analysis.
Solid-state electrodes offer advantages in terms of stability and ease of use compared to traditional liquid-junction electrodes.
Chlorpheniramine determination requires accurate and reliable analytical techniques.

Purpose of the Study:

To construct a new solid-state chlorpheniramine ion-selective electrode (ISE).
To investigate the electrochemical properties and performance of the newly developed electrode.
To evaluate the suitability of the electrode for the potentiometric determination of chlorpheniramine.

Main Methods:

Preparation of a silver/silver chloride (Ag/AgCl) solid-state electrode using urea-formaldehyde resin and potassium chloride (KCl).

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Construction of the chlorpheniramine ISE by utilizing the Ag/AgCl electrode as a substrate and incorporating a chlorpheniramine tetraphenylborate ion-pair complex as the active component.

Detailed characterization of the electrode's properties, including stability and potentiometric response.

Main Results:

A novel solid-state chlorpheniramine ISE was successfully fabricated.
The electrode exhibited good operational stability.
The developed electrode demonstrated efficacy in the potentiometric determination of chlorpheniramine.

Conclusions:

The newly constructed solid-state chlorpheniramine ISE, based on an Ag/AgCl substrate, is a viable analytical tool.
The electrode's stability and performance support its application in potentiometric analysis.
This work presents a promising method for the selective determination of chlorpheniramine.