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Updated: Jun 28, 2026

Measurement of Extracellular Ion Fluxes Using the Ion-selective Self-referencing Microelectrode Technique
Published on: May 3, 2015
How to understand the response mechanism of ion-selective electrodes
1Institute for General and Analytical Chemistry, Technical University, Budapest, Hungary.
Abstract:
The present study breaks with the earlier mechanism of electrode potential on basis of experimental investigations and theoretical considerations. It rejects that the transport through the membrane produces the electrode potential and definitely proves that the electrode potential is created via surface chemisorption; i.e., the electrode potential is produced by a surface reaction. The reaction centres can be acid-base groups or complex formation groups (e.g., valinomycin or other alkaline earth metal complexing ligands.
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