Intra-laboratory testing of method accuracy from recovery assays

Area of Science:

• Analytical Chemistry
• Laboratory Science

Background:

• Accurate analytical methods are crucial for reliable laboratory testing.
• Recovery assays are commonly used to assess method accuracy within a laboratory setting.

Purpose of the Study:

• To revise and present updated procedures for intra-laboratory accuracy testing of analytical methods.
• To discuss the application of recovery assays using spiked matrices and spiked samples.

Main Methods:

• Revision of existing intra-laboratory testing protocols.
• Development and discussion of procedures utilizing spiked matrices.
• Development and discussion of procedures utilizing spiked samples.

Main Results:

• Presented a revised framework for intra-laboratory accuracy testing.
• Detailed specific procedures for recovery assays with spiked matrices and samples.
• Provided a discussion on the practical application and implications of these methods.

Conclusions:

• The revised procedures enhance the accuracy assessment of analytical methods in laboratory settings.
• Utilizing spiked matrices and spiked samples offers a robust approach to validating method accuracy.