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Updated: Jun 28, 2026
![The Synthesis of [Sn10(Si(SiMe3)3)4]2- Using a Metastable Sn(I) Halide Solution Synthesized via a Co-condensation Technique](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F54498.jpg&w=3840&q=50)
The Synthesis of [Sn10(Si(SiMe3)3)4]2- Using a Metastable Sn(I) Halide Solution Synthesized via a Co-condensation Technique
Published on: November 28, 2016
Experimental design methodologies to optimize monobutyltin chloride determination by hydride generation gas phase
J Sanz1, M Pérez, M T Martínez
1Department of Chemistry (Analytical Chemistry), University of La Rioja, Obispo Bustamante 3, Logroño 26001, Spain.
Abstract:
A hydride generation gas phase molecular absorption spectrometry (HG-GPMAS) method for the determination of butyltin compound is optimized by experimental design. This method is based on the conversion of the butyltin chloride into gaseous monobutyltin hydride by adding a sodium tetrahydroborate (III) solution. The hydride generated is collected in a liquid nitrogen cryogenic trap. This is revolatilized, driven to the quartz flow cell and measured with GPMAS with diode array detection. A Plackett-Burmann design is used for the study of the factors that influence the absorption signal. The optimization of the parameters affecting the production and collection of the monobutyltin hydride is achieved using a central composite design. Partial least square (PLS), multiple linear regression (MLR) and univariate calibration are applied to the spectra obtained. The quality parameters (detection limits and precision) for the butyltin chloride are reported. An interference study is made.
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