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Methods of analysis of 4-quinolone antibacterials
F Belal1, A A Al-Majed, A M Al-Obaid
1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. ffbelal@ksu.edu.sa
Talanta
|October 31, 2008
Summary
This review summarizes analytical methods for 4-quinolone antibacterials. It covers techniques for analyzing these important drugs in various forms, including biological fluids.
Area of Science:
- Pharmacology and Pharmaceutical Analysis
- Medicinal Chemistry
Background:
- 4-quinolone antibacterials represent a critical class of therapeutic agents.
- Accurate analysis of these drugs is essential for quality control and therapeutic monitoring.
Purpose of the Study:
- To provide a comprehensive overview of analytical methodologies for 4-quinolone antibacterials.
- To consolidate information on methods for analyzing these drugs in pure form, pharmaceutical preparations, and biological matrices.
Main Methods:
- Literature review of analytical techniques.
- Compilation of methods reported in scientific publications.
- Categorization of analytical approaches based on application (drug substance, dosage form, biological fluid).
Main Results:
- Extensive coverage of analytical methods for 4-quinolone antibacterials.
- Inclusion of 270 references, indicating a thorough review.
- Methods applicable to diverse analytical scenarios are detailed.
Conclusions:
- A wide array of analytical techniques are available for 4-quinolone antibacterials.
- The review serves as a valuable resource for researchers and analysts in the field.
- Standardization and validation of methods are crucial for reliable results.
