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Electrochemical oxidation of cisatracurium on carbon paste electrode and its analytical applications
R F Torres1, M C Mochón, J C Sánchez
1Department of Analytical Chemistry, Faculty of Chemistry, University of Seville, 41012 Seville, Spain.
Abstract:
The electrochemical oxidation of cisatracurium was investigated by cyclic voltammetry and differential pulse voltammetry at a carbon paste electrode and the experimental parameters have been optimized in order to obtain the optimum analytical signal. A differential pulse voltammetric method with carbon paste electrode is described for the determination of cisatracurium with detection limit of 0.38 mug/ml and quantitation limit of 1.26 mug/ml. The proposed method was applied to determine the content of cisatracurium in human urine and human serum, obtaining accurate and precise results.
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