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Laser ablation in analytical chemistry-a review
Richard E Russo1, Xianglei Mao, Haichen Liu
1Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Laser ablation is a key technique for direct solid sampling in analytical chemistry, offering advantages like minimal sample prep and spatial analysis. This review covers recent advances in laser ablation coupled with inductively coupled plasma (ICP) systems.
Area of Science:
- Analytical Chemistry
- Materials Science
Background:
- Laser ablation is increasingly vital for direct solid sampling.
- It offers advantages over traditional methods, including direct solid analysis, no dissolution, reduced contamination, and micro-scale analysis.
Purpose of the Study:
- To review recent research on laser ablation for direct solid sampling.
- To focus on sample introduction into inductively coupled plasma (ICP) systems.
- To discuss advancements in experimental systems, calibration, optimization, and fractionation.
Main Methods:
- Review of contemporary experimental systems for laser ablation.
- Analysis of calibration and optimization strategies.
- Examination of fractionation phenomena in laser ablation.
- Summary of applications in diverse fields.
Main Results:
- Laser ablation coupled with ICP offers efficient direct solid sampling.
- Recent research has focused on understanding and optimizing the process.
- Key areas include experimental design, calibration, and managing elemental fractionation.
Conclusions:
- Laser ablation-ICP is a powerful technique for solid sample analysis.
- Continued research is refining its application for elemental composition and spatial distribution determination.
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