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Published on: August 22, 2017
Near infra-red reflectance spectroscopic determination of metformin in tablets
1Microanalytical Chem. Lab., National Research Centre, El-Tahrir Str., Dokki, Cairo, Egypt.
Abstract:
A rapid and simple near infra red reflectance spectroscopic method was described for determination of anti-diabetic tablets. Partial least squares method was applied to the Savitsky-Golay smoothed first derivative spectral data revealed over wavelength range 1000-2500 nm from 11 different pulverized tablet batches in 2-mm quartz cell. The results were agreed well with those obtained by the official British Pharmacopoiea 1998 UV assay of metformin.
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