[Fibrin tissue glue, its preparation and methods of application]

Fibrin glues used abroad are not imported to this country. Experience assembled abroad confirms the great possibilities to use them in the treatment of various tissues in all surgical disciplines. Attempts to apply this method must start by the elaboration of a similar system of glues from local raw materials. The effectiveness depends on the quality and concentration of individual components. The authors present a report on the possibility to elaborate a tissue glue from local resources using fibrinogen obtained from homologous blood or the patient's own blood. Fibrinogen USOL, Antilysin Spofa, Trombin Imuna and Calcium chloratum Spofa are readily available. The authors mention methods of the most suitable dilution of fibrinogen and methods how to obtain concentrated fibrinogen from autologous blood. They describe the preparation of both constituents of the glue for application and different methods of application. They evaluate advantages of different methods of administration. The authors describe also their own experience with the preparation and use of fibrin glue and experience with his own system of application. The advantages of fibrin tissue glue were proved by its use in different areas of surgery. Its particular importance was described in the treatment of injuries of parenchymatous organs.